PAC Dynamic is developing a heart model to guide treatment decisions
Choosing when to escalate heart failure treatment can be difficult when a patient's condition is changing. PAC Dynamic is developing software that aims to give clinicians a more individual picture of how that patient's heart is working.
A model built around the patient
Its Virtual Patient Simulator is intended to combine information about blood flow and pressure with a model of the heart's energy use. The aim is to help clinicians assess disease progression and consider how a patient might respond to medicines or mechanical support.
Founder and CEO Jonathan Grinstein told the Center for Data Innovation in March 2025 that the company was still seeking FDA clearance. Current clearance and clinical availability have not been confirmed.
Two potential customer groups
A July 2025 University of Chicago portfolio identified hospitals and medical-device companies as PAC Dynamic's target markets. For a hospital, the proposed decision-support tool addresses a clinical question; device companies could have a different interest in understanding how mechanical support interacts with an individual heart.
That gives the company two prospective customer groups for its physiological modeling, rather than a single consumer-facing app.